Colonic disease and the microbiota

Microb Health Dis 2020; 2 : e301
DOI: 10.26355/mhd_20207_301

  Topic: Gastroenterology     Category:

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Abstract

Microbiota is the set of microorganisms that compose our microbial community. The human microbiota comprises a vast collection of bacteria, viruses, fungi and protozoa that co-exist with us and establish physio-metabolic interactions with our cellular pathways. Qualitative and/or quantitative alterations of the microbiota, termed dysbiosis, has already been associated with a wide range of diseases and conditions, including inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), diverticular disease (DD), colorectal cancer (CRC), asthma, obesity, diabetes mellitus, hypertension, and cardiovascular disease. Microbiota changes in the intestinal lumen stimulate chronic inflammation possibly triggering disease in genetically predisposed individuals.

In this review we examined all studies published in the last year in order to provide the newest correlation between specific microbiota alterations and colonic disease, with a focus on future perspectives and strategies based on microbiota modulations.

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To cite this article

Colonic disease and the microbiota

Microb Health Dis 2020; 2 : e301
DOI: 10.26355/mhd_20207_301

Publication History

Submission date: 05 May 2020

Revised on: 14 May 2020

Accepted on: 23 Jun 2020

Published online: 07 Jul 2020