Colonic disease and the microbiota
Microb Health Dis 2020;
2
: e301
DOI: 10.26355/mhd_20207_301
Topic: Gastroenterology
Category: Review
Abstract
Microbiota is the set of microorganisms that compose our microbial community. The human microbiota comprises a vast collection of bacteria, viruses, fungi and protozoa that co-exist with us and establish physio-metabolic interactions with our cellular pathways. Qualitative and/or quantitative alterations of the microbiota, termed dysbiosis, has already been associated with a wide range of diseases and conditions, including inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), diverticular disease (DD), colorectal cancer (CRC), asthma, obesity, diabetes mellitus, hypertension, and cardiovascular disease. Microbiota changes in the intestinal lumen stimulate chronic inflammation possibly triggering disease in genetically predisposed individuals.
In this review we examined all studies published in the last year in order to provide the newest correlation between specific microbiota alterations and colonic disease, with a focus on future perspectives and strategies based on microbiota modulations.
In this review we examined all studies published in the last year in order to provide the newest correlation between specific microbiota alterations and colonic disease, with a focus on future perspectives and strategies based on microbiota modulations.
To cite this article
Colonic disease and the microbiota
Microb Health Dis 2020;
2
: e301
DOI: 10.26355/mhd_20207_301
Publication History
Submission date: 05 May 2020
Revised on: 14 May 2020
Accepted on: 23 Jun 2020
Published online: 07 Jul 2020
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